Dr. Kyle Williams and Dritan Agalliu, PhD present their research on the blood-brain barrier and immune cell infiltration in PANDAS. They discuss the historical link between infections and neuropsychiatric symptoms, and how microglial activation relates to obsessive-compulsive behaviors. Their studies reveal the impact of infections on endothelial and microglial cells, highlighting IL-17A’s role in brain pathology and potential therapeutic targets.
Presentation 8-A: Lightning Rounds – Identification of Key Cytokines in the Pathogenesis of OCD and PANDAS
Updated: July 23, 2025 by bmanfull@comcast.net
Dr. Kyle Williams and Dritan Agalliu, PhD present their research on the blood-brain barrier and immune cell infiltration in PANDAS. They discuss the historical link between infections and neuropsychiatric symptoms, and how microglial activation relates to obsessive-compulsive behaviors. Their studies reveal the impact of infections on endothelial and microglial cells, highlighting IL-17A’s role in brain pathology and potential therapeutic targets.
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